Table 1.
Body weight, liver weight and total fat pad weight of wild type, heterozygous and homozygous BCMO1-deficient mice fed β-carotene diet. Numbers represents mean ± SD for 4–5 animals/group. Baseline measurements were carried out at 6 weeks of age and β-carotene diet (100 μg β-carotene/g diet) was provided to mice for 4 and 7 weeks. Body, liver, and fat pad weights were not statistically different among all three genotypes at all time points.
| Male | Female | |||||
|---|---|---|---|---|---|---|
| Baseline | 4 weeks | 7 weeks | Baseline | 4 weeks | 7 weeks | |
| Weight (g)
| ||||||
| WT | 22.41 ± 0.81 | 26.29 ± 2.82 | 28.98 ± 1.66 | 17.88 ± 1.45 | 20.29 ± 1.16 | 20.05 ± 1.03 |
| Het | 22.67 ± 1.25 | 27.40 ± 2.79 | 28.15 ± 5.89 | 17.65 ± 0.66 | 18.88 ± 1.82 | 21.72 ± 0.94 |
| KO | 21.11± 1.49 | 25.93 ± 4.87 | 30.06 ± 3.67 | 18.18 ± 0.76 | 18.43 ± 1.38 | 20.17 ± 2.19 |
|
| ||||||
| Liver weight (g)
| ||||||
| WT | 1.36 ± 0.28 | 1.13 ± 0.13 | 1.07 ± 0.15 | 0.95 ± 0.11 | 0.95 ± 0.09 | 0.84 ± 0.08 |
| Het | 1.28 ± 0.19 | 1.21 ± 0.11 | 0.99 ± 0.25 | 0.87 ± 0.06 | 0.74 ± 0.14 | 0.86 ± 0.04 |
| KO | 1.14 ± 0.24 | 1.11 ± 0.22 | 1.15 ± 0.06 | 0.93 ± 0.23 | 0.89 ± 0.16 | 0.78 ± 0.14 |
|
| ||||||
| Fat pads weights (g)
| ||||||
| WT | 0.60 ± 0.15 | 1.37 ± 0.54 | 1.64 ± 0.28 | 0.36 ± 0.07 | 0.55 ± 0.15 | 0.75 ± 0.34 |
| Het | 0.71 ± 0.27 | 1.52 ± 0.59 | 1.78 ± 1.13 | 0.53 ± 0.10 | 0.57 ± 0.27 | 0.86 ± 0.21 |
| KO | 0.60 ± 0.19 | 1.29 ± 0.80 | 1.67 ± 0.73 | 0.66 ± 0.26 | 0.58 ± 0.29 | 0.75 ± 0.12 |