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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: Cell Metab. 2007 Sep;6(3):195–207. doi: 10.1016/j.cmet.2007.08.001

Figure 5. Fat-Selective Blockade of Adipose Produces Murine Obesity and Hyperglycemia.

Figure 5

(A) aP2-AdpC1 construct.

(B, C) Average weights (B) and average NMR fat content (C) of aP2-AdpC1 transgenic and non-transgenic founders (n = 10).

(D) Average weights of inguinal (I), mesenteric (M), and perigonadal (G) WAT depots as well as the indicated organs from aP2-AdpC1 transgenic mice and littermate controls. (n = 10)

(E) Histological analyses of control and aP2-AdpC1 inguinal (Ing, top) and perigonadal (Gon, bottom) WAT.

(F) Food intake of aP2-AdpC1 transgenic mice and littermates.

(G) GTTs of aP2-AdpC1 mice and control littermates. Analyses in panels B–G on 8-month old mice.

*p < 0.05, **p < 0.01; N/S not significant by t-test. Error bars represent SEM.