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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Brain Res. 2008 Feb 16;1207:225–236. doi: 10.1016/j.brainres.2008.01.095

Fig. 4. Double immunostained sections of hippocampal CA1 neurons in untreated 6 month 3×Tg-AD mice.

Fig. 4

A. Double immunostained sections for NU-1 and MC1 show diffuse MC1 immunoreactivity (brown) extending into the apical dendrite of neurons with granular perikaryal NU-1 (red, asterisks), original magnification × 945. B. Double immunostained sections for NU-1 and CP-13 shows diffuse CP-13 immunoreactivity (brown) extending into the apical dendrite of neurons with granular perikaryal NU-1 (red, asterisks), original magnification × 945. C. Double immunostained sections for NU-1 and AT8 shows granular AT8 immunoreactivity (brown) in occasional neurons, while neighboring neurons show granular perikaryal NU-1 (red, asterisk), original magnification × 945. D. Double immunostained sections for NU-1 and PHF-1 shows dense aggregates of PHF-1 immunoreactivity (brown) in the perikaryon and dendrite of occasional neurons, while neighboring neurons show granular perikaryal NU-1 (red, asterisk), original magnification × 945. E. Double immunostained sections for NU-1 and CP-13 show diffuse CP-13 immunoreactivity (brown) extending into the apical dendrites and lush dendritic arbors of neurons with granular perikaryal NU-1 (red, asterisks), original magnification × 945.