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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: Bioconjug Chem. 2007 Jun 13;18(4):1148–1154. doi: 10.1021/bc070008z

Figure 1.

Figure 1

(A) Molecular mass distributions of the starting material E5.NH2 dendrimer and (B), the E5.(NHAc)72(NHB)8(NHSAH)35(NHSAcRGD)4 nanodevice shown by their RI signals (insert - MALLS data). Fit of RI signals was performed using Gaussian deconvolution of SEC chromatograms using PeakFit software. The starting material contains (A1) (E5.NH2)2 dimers (16.42%); (A2) E5.NH2 generation five dendrimers (80.42%), and (A3) a small amount of trailing generation E4.NH2 (3.15%). Average molecular mass of Mn=27280, Mw=30280 with a polydispersity of Mw/Mn = 1.110 were obtained for this material. The final product (B) contains modified dimers (B1=16.32%); modified E5 derivatives (B2=80.22%), and a small amount of modified trailing generation (B3=3.46%). (Respective molecular masses calculated from PeakFit are Mn=34080, Mw=38067, and Mw/Mn = 1.117).