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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Arch Gen Psychiatry. 2008 Feb;65(2):179–188. doi: 10.1001/archgenpsychiatry.2007.19

Table 2.

Behavioral, scalp ERP, and LORETA findings

MDD Subjects Comparison Subjects Group Effects

Mean SD Mean SD p-valuea

A. Behavioral Datab
 Post-correct accuracy 0.91 0.08 0.92 0.05 n.s.
 Post-error accuracy 0.87 0.08 0.92 0.06 0.005

 Post-correct RT 340.12 82.29 322.34 54.40 n.s.
 Post-error RT 380.95 97.21 354.89 68.23 n.s.
B. Scalp ERP data (μV)c
 ERN −2.74 1.83 −1.42 1.69 0.01
 CRN 0.20 1.80 1.33 2.01 n.s.

 Early Pe 3.58 2.33 3.42 2.40 n.s.
 Late Pe 3.61 2.40 4.29 3.52 n.s.
C. LORETA datad
 rACC (BA 32) −3.50 0.09 −3.74 0.18 0.00003

Abbreviations: ACC, anterior cingulate cortex; BA, Brodmann area; CRN, correct-response negativity; ERN, error-related negativity; ERP, event-related potential; LORETA, low-resolution electromagnetic tomography; MDD, major depressive disorder; Pe, error positivity; RT, reaction time.

a

Data are presented as mean (SD).

b

Findings from unpaired t tests (postcorrect RT, posterror RT, early PE, and late PE) or post hoc Newman-Keuls tests (postcorrect accuracy, posterror accuracy, ERN, and CRN) are reported.

c

Posterior adjustment effects were restricted to trials following incongruent trials. Comparison subjects: n=20; patients with MDD: n=20.

d

Mean amplitudes (averaged across Fz, FCz, Cz, and Pz) for incongruent trials. Comparison subjects: n=18; patients with MDD: n=18.

e

Current density, 80 milliseconds after error for incongruent trials. Comparison subjects: n=18; patients with MDD: n=18.