. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: J Nucl Med. 2008 Aug 14;49(9):1414–1421. doi: 10.2967/jnumed.107.049619

Table 1.

Global values of CBF and of K* for arachidonic acid in healthy control and Alzheimer disease subjects, before and after correction for partial volume error (PVE). Values were calculated from mean values from 90 hemispheric regions identified in a stereotactic atlas (35), and were compared by two-tailed t-tests

Group		PVE-Uncorrected		PVE-Corrected
		CBF	K*	CBF	K*
		mL/100g/min	μL/min/mL	mL/100g/min	μL/min/mL
Control	Number^a	7	9	7	9
	Mean ± SD CV %	38.0 ± 5.3 (13.8)	4.7 ± 0.6 (12.0)	61.6 ± 10.1 (16.4)	6.9 ± 0.8 (11.9)
AD	Number^a	6	8	6	8
	Mean ± SD CV %	27.1 ± 7.6^* (28.1)	5.5 ± 0.8^* (15.2)	48.3 ± 14.0 (28.9)	8.7 ± 1.4^** (15.7)
Diff %		-28.6	18.3	-21.5	26.4

Differs significantly from control mean by 2-tailed t-test, *p ≤ 0.05

^**

p ≤ 0.01

Number of CBF scans is fewer than K* scans because of failure of some CBF scans