. Author manuscript; available in PMC: 2009 Jun 1.

Published in final edited form as: Am Heart J. 2008 Feb 21;155(6):992–997. doi: 10.1016/j.ahj.2008.01.007

Table III.

Cross-sectional associations of MMP-9 and BNP with LVEDDI (cm/m²)

	Univariate		Multivariate^*
			MMP-9 alone		BNP-Alone		MMP-9 and BNP
	Coefficient	p-value	Coefficient	p-value	Coefficient	p-value	Coefficient	p-value
MMP-9, log ng/mL	0.007	0.9	0.049	0.30	-	-	0.026	0.6
BNP, log pg/mL	0.081	<.001	-	-	0.076	<.001	0.075	<.001

Adjusted for age, gender, race, BMI, heart failure duration, NYHA class, creatinine clearance, mean arterial pressure, and use of aldosterone antagonists, beta-blockers, and cardiac resynchronization therapy. Other covariates showed minimal associations in univariate models (P > 0.1) and were not included in multivariate models.