Table IV.

Cross-sectional associations of MMP-9 and BNP with EF (%)

	Univariate		Multivariate*
			MMP-9 alone		BNP-Alone		MMP-9 and BNP
	Coefficient	p-value	Coefficient	p-value	Coefficient	p-value	Coefficient	p-value
MMP-9, log ng/mL	−1.3	0.17	−1.4	0.14	-	-	−1.1	0.2
BNP, log pg/mL	−1.7	<.001	-	-	−1.6	<.001	−1.6	0.002

^*Adjusted for age, gender, race, BMI, heart failure duration, ischemic etiology, NYHA class, diabetes mellitus, creatinine clearance, mean arterial pressure, and use of aldosterone antagonists, beta-blockers, and cardiac resynchronization therapy. Other covariates showed minimal associations in univariate models (P > 0.1) and were not included in multivariate models.