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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Am Heart J. 2008 Feb 21;155(6):992–997. doi: 10.1016/j.ahj.2008.01.007

Table V.

Association of baseline MMP-9 and BNP with risk of subsequent cardiac hospitalization or death

Univariate
Multivariate*
MMP-9 alone BNP-Alone MMP-9 and BNP
Hazard Ratio p-value Hazard Ratio p-value Hazard Ratio p-value Hazard Ratio p-value
MMP-9, log ng/mL 1.14 0.19 1.02 0.8 - - 0.98 0.9
BNP, log pg/mL 1.28 <.001 - - 1.14 0.02 1.15 0.02
*

Adjusted for age, gender, race, BMI, heart failure duration, ischemic etiology, NYHA class, creatinine clearance, EF, LVEDDI, and use of cardiac resynchronization and defibrillators. Other covariates showed minimal associations in univariate models (P > 0.1) and were not included in multivariate models.