Table 3.
Comparison of High- and Moderate-Dose MST on Cognitive Effects
| Task1 | High-Dose MST | Mod-Dose MST | Statistic | p-value | Effect Size (Cohen’s d) |
|---|---|---|---|---|---|
| Task 1 | (3 subjects) | (2 subjects) | |||
| Time to Wake/Begin (min)2 | 14 (11) | 6 (2) | T=−3.56, df=260 | P=0.0004 | Medium (0.45) |
| Time to Completion (min) | 3 (2) | 3 (2) | NS | -- | |
| Accuracy (%) | 76.0% (18.0) | 85.4% (15.3) | NS | -- | |
| Task 2 | (3 subjects) | (2 subjects) | |||
| Time to Completion (min) | 5.2 (7.9) | 8.2 (8.8) | NS | -- | |
| Accuracy (%) | 80.2% (22.7) | 54.2% (29.1) | F=−3.86, df=600 | P=0.0001 | Medium (0.45) |
| Task 3 | (2 subjects) | (2 subjects) | |||
| Old List Accuracy (%) | 63.8% (20.0) | 43.6% (24.7) | T=1.98, df=293 | P=0.0488 | Medium (0.41) |
| New List Accuracy (%) | 39.1% (25.9) | 29.5% (19.8) | NS | -- |
1
All values are expressed as mean (SD) unless otherwise noted
2
The time to wake/begin showed a study-by-condition interaction in which both the MST and Sham conditions showed lengthier times in the new study relative to the old study.