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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: J Immunol. 2008 Jul 15;181(2):1299–1306. doi: 10.4049/jimmunol.181.2.1299

Table II.

Percentage of mutations in RGYW/WRCY and WA/TW motifs.

AICDA−/−
Normal Donors
NP P NP P
WRCY 1.5/43* 13.8/124 98.1/627 756.7/4864
3% 11% 16% 16%
RGYW 4.5/43* 30.3/124 152.4/627 1285.9/4864
10% 24% 24% 26%
WA 4.5/43* 25.5/124 140.4/627 888.5/4864
10% 21% 22% 18%
TW 1.5/43 9/124 73.7/627 490.5/4864
4% 7% 12% 10%

The enumeration of nucleotides was adjusted for nucleotides that occupy a position in more than one motif or ambiguous motifs. This calculation therefore, can assign a fraction of a mutation for a given motif.

*

Significant (p≤.05) difference between AICDA−/− and ND

significant (p<.008) difference between WRCY and RGYW

significant (p<.009) difference between WA and TW.