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. Author manuscript; available in PMC: 2009 Jul 10.
Published in final edited form as: J Med Chem. 2008 Jun 5;51(13):3731–3741. doi: 10.1021/jm701239a

Figure 10.

Figure 10

Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide) (1X7A). The CF3 of the pyrazole ligand interacts tightly with the cationic terminus of the Arg143 side chain. Units for numerical values are Å.