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. Author manuscript; available in PMC: 2009 Jul 10.
Published in final edited form as: J Med Chem. 2008 Jun 5;51(13):3731–3741. doi: 10.1021/jm701239a

Figure 8.

Figure 8

H-Ras 166 in 50% 2,2,2 triflouroethanol (1P2S) sequesters the CF3 group of a solvent molecule between Arg97 and Lys101 side chains by bidentate and monodentate hydrogen bonds, respectively. Distances are between F---N atoms. Units for numerical values are Å.