Table 1. Sustained Response During Weeks 18-36 for Patients who had not Achieved Sustained Response by Week 12.
Treatment Arm | Number (%) of Patients who had not Achieved Sustained Response by Week 12 | Week 18-36 Sustained Response Status | n (%) |
---|---|---|---|
COMB | 25 of 86 (29.1%) | Sustained Response
Possible Sustained Response Non-Sustained Response |
15 (60.0%)
5 (20.0%) 5 (20.0%) |
FLX | 26 of 80 (32.5%) | Sustained Response
Possible Sustained Response Non-Sustained Response |
12 (46.2%)
4 (15.4%) 10 (38.5%) |
CBT | 44 of 76 (57.9%) | Sustained Response
Possible Sustained Response Non-Sustained Response |
25 (56.8%)
9 (20.5%) 10 (22.7%) |
All Active Tx | 95 of 242 (39.3%) | Sustained Response
Possible Sustained Response Non-Sustained Response |
52 (54.7%)
18 (18.9%) 25 (26.3%) |
Note: Week 18-36 Sustained Response Status indicates whether the patient achieved Sustained Response at any point during the period. If the patient had multiple response classifications across the period, the best response status was counted. The clinical ordering of response status from best to worse is: Sustained Response (i.e., 2 consecutive ratings of “full responder,” defined as CGI-I = 1 or 2), Possible Sustained Response (i.e., one rating of “full responder” either at the end of Stage III or followed by missing assessments only), and Non-Sustained Response (all other responder patterns).