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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: Neuroscience. 2008 Mar 26;153(4):963–974. doi: 10.1016/j.neuroscience.2008.03.042

Fig. 5.

Fig. 5

Effect of LED treatment on cytochrome oxidase activity and cellular ATP content in cortical neurons exposed to KCN and 1–4 times of LED treatment. A, C, E: Quantification of cytochrome oxidase activity in cultured primary neurons after 1–4 times of LED treatment and KCN exposure for 24 h, 3 days, and 5 days, respectively. Two times of LED treatment resulted in the highest cytochrome oxidase activity as compared to other LED regimens. B, D, F: levels of cellular ATP content in neurons after 24 h, 3 days, and 5 days of KCN exposure, respectively, and 1–4 times of LED treatment. LED treatment twice a day was most effective in restoring ATP contents close to, though not reaching control levels. G: Cellular ATP content in cortical neurons after twice a day LED treatment for 1, 3 and 5 days. LED treatment significantly increased cellular ATP content compared to controls. All *P values were compared to controls: *, P < 0.05, **, P < 0.01, ***, P < 0.001. All +P values were compared to KCN alone: +, P < 0.05, ++, P < 0.01, +++, P < 0.001.