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. 2008 Oct 14;9:433. doi: 10.1186/1471-2105-9-433

Table 2.

Gene-finding performance for various algorithms.

Gene Transcript Exon
ALL initial internal terminal single

sn% sp% sn% sp% sn% sp% sn% sp% sn% sp% sn% sp% sn% sp%

Augustus 47.0 50.9 37.6 50.9 70.8 78.8 53.5 66.4 77.6 81.8 70.9 83.2 61.9 72.

CONTRAST 48.8 51.9 39.2 51.9 69.7 80.8 57.4 70.6 74.2 84.6 69.7 80.8 68.9 78.0

Geneid 35.9 41.4 29.3 41.4 65.7 71.4 47.0 60.9 75.6 73.9 59.2 72.8 54.6 73.7

Genie 40.7 50.0 31.9 50.0 58.2 77.9 44.1 63.7 63.1 82.7 58.8 80.2 58.7 68.8

Genscan 31.4 35.7 24.9 35.7 61.3 61.6 42.4 54.6 70.8 61.6 54.1 65.9 58.7 76.9


Evigan-5g 54.6 58.9 43.8 58.9 73.7 84.4 61.0 74.6 78.7 87.5 72.9 84.6 70.7 85.6


ReRanker-5g 57.6 62.1 46.1 62.1 74.2 85.4 61.8 75.9 79.0 88.5 73.9 85.9 71.6 86.3


GeneWise 29.4 31.0 25.0 31.0 58.3 73.9 41.8 56.7 69.5 90.9 48.5 59.4 32.3 30.6

Augustus+ 53.3 57.0 43.5 57.0 73.0 81.1 58.3 72.2 79.2 84.0 71.6 83.3 65.2 73.0

Evigan-6g 56.3 60.7 45.1 60.7 74.7 85.2 61.4 75.4 80.2 88.3 73.5 85.7 70.5 84.7

Performance on the entire D. melanogaster test set of 7777 loci (see Table 1). Augustus, CONTRAST, Geneid, Genie and Genscan are ab initio predictors used as evidence sources for Evigan-5g. ReRanker-5g selects among K-best gene models produced by Evigan-5g with cross-species information. GeneWise, Augustus+ and Evigan-6g are other comparative gene predictors or approaches. Bold indicates where ReRanker-5g outperforms Evigan-5g; italics indicates where other comparative approaches outperform ReRanker-5g (see text).