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. Author manuscript; available in PMC: 2009 Nov 10.
Published in final edited form as: J Comp Neurol. 2008 Nov 10;511(2):271–285. doi: 10.1002/cne.21835

Fig. 6.

Fig. 6

Systemic treatment with SL327 prevents the structural abnormalities induced by D1-priming. Rats were administered 100 mg/kg ip SL327 (sSL) or vehicle (sVeh), 30 min prior to each weekly dose of SKF-38393 and sacrificed 7 days following the final treatment. (A-C), Reconstructed confocal images of GFP-positive dendrites in Sham-sVeh-SKF (A), Les-sVeh-SKF (B), and Les-sSL-SKF (C) rat mPFC. Scale bars, 50 μm. (D) Linearity index of dendritic elements in GFP-expressing mPFC of Sham-sVeh-SKF (black bars), Les-sVeh-SKF (open bars), and Les-sSL-SKF rats (gray bars). Represented are means ± S.E.M. *** p < 0.0001 vs. Sham-sVeh-SKF. (E) Diameter of dendritic elements in mPFC. The format is the same as in D. ** p < 0.005, and * p < 0.05 vs. Sham-sVeh-SKF; ANOVA with Fisher’s PLSD.