Table 1.

Effects of D₁ priming on linearity index and diameter of GFP-expressing dendrites in mPFC

	Average Contour Measurement	Average End-to-end Measurement	Linearity Index	Diameter
Primary shafts
Sham-SKF	154.98 ± 3.93	154.37 ± 4.03	1.004 ± 0.001	2.44 ± 0.31
Les-SKF	151.47 ± 6.10	148.55 ± 6.26	1.019 ± 0.002**	2.29 ± 0.40
Layer I branches
Sham-SKF	47.93 ± 2.59	45.67 ± 2.49	1.052 ± 0.004	0.77 ± 0.06
Les-SKF	46.69 ± 1.63	44.01 ± 1.57	1.065 ± 0.008	1.11 ± 0.09*
Layer II-III obliques
Sham-SKF	30.16 ± 0.94	28.07 ± 0.83	1.076 ± 0.007	0.76 ± 0.02
Les-SKF	30.31 ± 1.43	28.09 ± 1.42	1.085 ± 0.009	1.06 ± 0.12*
Layer V obliques
Sham-SKF	24.23 ± 2.12	22.55 ± 1.88	1.075 ± 0.014	0.73 ± 0.02
Les-SKF	27.71 ± 0.98	25.76 ± 0.83	1.077 ± 0.006	0.79 ± 0.05

To obtain the linearity index, the contour length of each dendrite was divided by the length of a straight line from one end of the dendrite to the other. Diameter was measured at 2-3 different sites along the visible length and averaged for each dendrite. See Methods for total numbers of dendrites measured per animal. Each measurement was averaged per animal and data are expressed as the mean ± SEM of all animals per group. Sham-SKF, n = 3-4. Les-SKF, n = 5-6. Rats were perfused at day 7 after the final treatment with SKF-38393.

^**p < 0.0001

^*p < 0.005 vs. Sham-SKF.