Table 4.
Exploratory analysis of gender effect across each gene
| Gene | Allele | Male | Female | χ2 | P-value | ||
|---|---|---|---|---|---|---|---|
| COMT | T | NT | T | NT | |||
| rs737866 | C | 114 | 133 | 65 | 50 | 3.37 | 0.066 |
| rs174675 | C | 111 | 116 | 70 | 59 | 0.94 | 0.330 |
| rs740603 | A | 156 | 135 | 71 | 80 | 1.72 | 0.188 |
| rs2239393 | A | 160 | 114 | 58 | 63 | 3.71 | 0.054 |
| rs4680 | A | 162 | 114 | 77 | 78 | 3.26 | 0.071 |
| rs4646316 | C | 155 | 112 | 51 | 50 | 1.69 | 0.192 |
| rs165774 | A | 124 | 97 | 76 | 72 | 0.81 | 0.368 |
| rs174696 | C | 107 | 98 | 43 | 56 | 2.05 | 0.152 |
| rs174699 | C | 31 | 28 | 11 | 17 | 1.33 | 0.247 |
| rs9332377 | C | 85 | 83 | 46 | 42 | 0.06 | 0.798 |
|
| |||||||
| MAOA | |||||||
|
| |||||||
| rs5906957 | A | 49 | 56 | 26 | 30 | 0.001 | 0.977 |
| rs12843268 | A | 60 | 61 | 27 | 34 | 0.46 | 0.497 |
| rs3027399 | C | 22 | 20 | 20 | 8 | 2.54 | 0.111 |
| rs3027400 | G | 60 | 58 | 36 | 27 | 0.65 | 0.418 |
| rs2072743 | C | 65 | 65 | 40 | 28 | 1.39 | 0.237 |
| rs2239448 | C | 60 | 58 | 35 | 27 | 0.51 | 0.474 |
| rs1801291 | C | 57 | 58 | 35 | 27 | 0.76 | 0.381 |
| rs3027407 | A | 58 | 60 | 27 | 36 | 0.65 | 0.418 |
| rs12843533 | C | 19 | 21 | 10 | 9 | 0.13 | 0.712 |
| rs6609257 | A | 74 | 74 | 40 | 34 | 0.32 | 0.568 |
| rs3027415 | C | 50 | 51 | 28 | 25 | 0.15 | 0.695 |
|
| |||||||
| NET | |||||||
|
| |||||||
| rs36030 | C | 69 | 70 | 35 | 45 | 0.71 | 0.401 |
| rs17306977 | A | 59 | 77 | 37 | 32 | 1.92 | 0.165 |
| rs3785143 | T | 55 | 46 | 38 | 18 | 2.68 | 0.101 |
| rs1532701 | A | 165 | 153 | 69 | 83 | 1.73 | 0.187 |
| rs192303 | C | 133 | 130 | 78 | 62 | 0.96 | 0.324 |
| rs36024 | A | 141 | 139 | 69 | 62 | 0.19 | 0.661 |
| rs36021 | A | 136 | 131 | 60 | 67 | 0.46 | 0.493 |
| rs3785151 | C | 73 | 84 | 32 | 32 | 0.22 | 0.636 |
| rs36020 | C | 55 | 75 | 45 | 30 | 5.95 | 0.014 |
| rs3785152 | C | 60 | 39 | 28 | 25 | 0.85 | 0.354 |
| rs40147 | A | 113 | 138 | 60 | 57 | 1.25 | 0.262 |
| rs1814269 | A | 136 | 152 | 81 | 65 | 2.64 | 0.104 |
| rs10521329 | A | 99 | 98 | 48 | 55 | 0.36 | 0.548 |
| rs11568324 | C | 9 | 3 | 4 | 1 | 0.05 | 0.824 |
| rs3785157 | C | 135 | 155 | 64 | 69 | 0.09 | 0.764 |
| rs5568 | A | 132 | 120 | 64 | 80 | 2.31 | 0.128 |
| rs5569 | A | 121 | 104 | 49 | 59 | 2.06 | 0.151 |
| rs998424 | A | 154 | 135 | 68 | 67 | 0.31 | 0.575 |
| rs15534 | C | 91 | 95 | 51 | 36 | 2.23 | 0.135 |
| rs42460 | A | 46 | 40 | 28 | 23 | 0.02 | 0.872 |
| rs16955708 | C | 88 | 87 | 44 | 38 | 0.25 | 0.614 |
| rs12596924 | G | 93 | 92 | 52 | 55 | 0.07 | 0.783 |
| rs1948773 | A | 54 | 54 | 31 | 25 | 0.42 | 0.515 |
| rs258099 | C | 118 | 120 | 66 | 74 | 0.21 | 0.647 |
|
| |||||||
| SERT | |||||||
|
| |||||||
| rs11080121 | A | 155 | 147 | 73 | 71 | 0.02 | 0.901 |
| rs140700 | A | 52 | 55 | 20 | 19 | 0.08 | 0.774 |
| rs12150214 | C | 94 | 84 | 42 | 42 | 0.18 | 0.671 |
| rs2066713 | T | 152 | 128 | 74 | 74 | 0.71 | 0.398 |
| rs4251417 | A | 56 | 54 | 32 | 32 | 0.01 | 0.907 |
| rs16965628 | C | 39 | 36 | 22 | 17 | 0.2 | 0.654 |
| rs7214991 | C | 157 | 133 | 69 | 82 | 2.83 | 0.092 |