Fig. 2.

In ESI of native cytochrome c, juxtaposition of the ε-N⁺H₃ of Lys-79 versus the amide oxygen of Tyr-48. (A) Local native structure just after complete H₂O loss. (B) Ten picoseconds later, the near-instantaneous collapse forming ionic hydrogen bonds between these adjacent (in structure, but not sequence) sites. [Reproduced with permission from ref. 20 (Copyright 2008, Wiley).]