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. 2000 May 9;97(10):5610–5615. doi: 10.1073/pnas.97.10.5610

Figure 2.

Figure 2

ED increases AP-independent vesicular release of glutamate. (A1) Sample traces of AMPA receptor-mediated miniature EPSCs at −60 mV, in the presence of dAPV and picrotoxin at two different time resolutions. (A2) Time-course plot of the increase in mEPSC frequency during ED. (A3) Cumulative plot for interevent intervals. (Inset) Expanded time scale; n = 5. (B1) Inhibition of vesicular release with TeNT limits the increase in [glu]o during ED. (B2) Summary histogram of normalized values of the dAPV-sensitive current after 9 min of ED for Ctl and TeNT-treated cultures; n = 9.