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. 2000 May 9;97(10):5610–5615. doi: 10.1073/pnas.97.10.5610

Figure 3.

Figure 3

Increased vesicular release is not sufficient to account for increased [glu]o. (A) (Top) Increasing mEPSC frequency with sucrose under Ctl conditions induces negligible outward current. (Bottom) After blockade of glutamate uptake with TBOA, sucrose induces a large NMDAR-mediated outward current (different cell from above). (B) The frequency of mEPSCs is not significantly different after 2 min treatment with sucrose or 6 min of ED. Values are normalized to mEPSC frequency during Ctl; n = 8. (C) Pooled data for the amplitude of NMDAR-mediated currents induced by sucrose alone and by sucrose in presence of TBOA; n = 6.