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MPTP-induced dopaminergic cell loss in +/+, +/mk, and mk/mk mice. (A) Peroxidase/DAB immunohistochemistry for TH on coronal mesencephalic sections from saline-injected and MPTP-intoxicated +/+ (WT) and mk/mk mice. The SNpc is delineated. (Scale bar: 100 μm.) (B) Bar graph of stereological counts of TH-positive cells in the SNpc of saline- and MPTP-injected mice (7 days after MPTP intoxication). **, P < 0.01.
