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. 2008 Nov 14;105(47):18578–18583. doi: 10.1073/pnas.0804373105

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© 2008 by The National Academy of Sciences of the USA

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Fig. 4. — Amphetamine-induced rotational behavior and dopaminergic cell loss in +/+, +/b, and b/b rats after 6-OHDA intrastriatal injection. (A) Bar graph of amphetamine-induced rotational behavior 7 days after 6-OHDA injection in wild-type Fischer 344 (+/+), heterozygous (+/b), and Belgrade (b/b) rats. (B) Bar graph of stereological nigral TH-positive DN counts in sham-injected and 6-OHDA-injected rats 14 days after injection. **, P < 0.01. (C) Representative peroxidase/DAB immunohistochemistry for TH on coronal mesencephalic sections +/b (control) and b/b (Belgrade) rats 14 days after 6-OHDA injection. (Scale bar: 300 μm.) (Insets) Enlargements of the outlined areas.