. 2008 Oct 27;105(47):18114–18119. doi: 10.1073/pnas.0801849105

Table 1.

Intramolecular kinetic isotope effects associated with the room-temperature C–H(D) bond activation of CH₂D₂ by selected ligated metal cations in the gas phase

Metal hydrides and halides	KIE	Metal oxides	KIE
PtBr⁺ + CH₄ → PtCH₃⁺ + HBr	1.03	V₄O₁₀⁺ + CH₄ → V₄O₁₀H⁺ + CH₃^•	1.35
PtH⁺ + CH₄ → PtCH₃⁺ + H₂	1.11	MnO⁺ + CH₄ → MnOH⁺ + CH₃^•	1.8
PtCl⁺ + CH₄ → PtCH₃⁺ + HCl	1.16	MgO⁺ + CH₄ → MgOH⁺ + CH₃^•	2.1
PtBr⁺ + CH₄ → BrPtCH₂⁺ + H₂	1.25	MoO₃⁺ + CH₄ → MoO₃H⁺ + CH₃^•	2.3
PtCl₂⁺ + CH₄ → ClPtCH₃⁺ + HCl	1.38	OFeOH⁺ + CH₄ → FeOH⁺ + CH₃OH	3.5
NiF⁺ + CH₄ → NiCH₃⁺ + HF	3.3	FeO⁺ + CH₄ → FeOH⁺ + CH₃^•	4.6