Table 1. Suppression of PEV and TPE by cloned Su(var) genes.
Gene | Allele | Mutation | PEV | TPE |
Su(var)3-9 | 3-906 | null | +++ | ++a |
3-91 | R493Q (SET domain) | +++ | ++b | |
3-92A5 | P element insertion | +++ | − | |
3-9309 | C462Y (preSET domain) | +++ | ++ | |
3-9311 | G521D (SET domain) | +++ | ++ | |
3-9318 | S616L (postSET domain) | +++ | + | |
3-9324 | C428Y (preSET domain) | +++ | − | |
3-9325 | P582Q (SET domain) | +++ | + | |
3-9330 | D536N (SET domain) | +++ | +++ | |
3-9376 | C421S (preSET domain) | +++ | + | |
Hdac1 | Hdac1303 | C98Y | +++ | + |
Hdac1313 | R30C | +++ | + | |
Hdac1326 | P204S | +++ | +++ | |
abo | abo | Point mutation | + | −b |
HP1a | Su(var)2-55 | Point mutation | +++ | −c |
Su(var)2-54 | Point mutation | +++ | − | |
Deficiency | Df: 28E4-7; 29B2-C1 | +++ | −b | |
puc | puc | P element insertion | +++ | −b |
Su(var)2-10 | Su(var)2-102 | Point mutation | +++ | ++b |
Su(var)2-10 | Df: 45A6-7; 45E2-3 | ++ | ++b | |
Su(var)3-7 | Deficiency | small deficiency | +++ | −a |
Deficiency | Df: 87E1; 87F12 | +++ | +b |
Unless otherwise indicated mutations were generated in this laboratory.
gift from G. Reuter.
Bloomington Stock Center.
gift from J. Mason.