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. 1990 Jul;58(7):2067–2070. doi: 10.1128/iai.58.7.2067-2070.1990

Production of toxic shock syndrome-like illness in rabbits by Staphylococcus aureus D4508: association with enterotoxin A.

B D McCollister 1, B N Kreiswirth 1, R P Novick 1, P M Schlievert 1
PMCID: PMC258777  PMID: 2365451

Abstract

Staphylococcus aureus D4508, obtained from a patient with nonmenstrual toxic shock syndrome (TSS), produced enterotoxin A while not making other known enterotoxins or TSS toxin 1. Concentrated culture fluids of the organism, administered subcutaneously in miniosmotic pumps, induced TSS-like symptoms (four of six animals succumbed). Identical culture fluids pretreated with anti-enterotoxin A serum failed to induce symptoms except for fever (none of six animals succumbed). Purified staphylococcal enterotoxin A also had the ability to induce TSS-like symptoms. These data suggest that enterotoxin A is the major TSS-associated toxin made by strain D4508.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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