Table 1.
pulsar analysis of basal corticosterone
| Treatment | Plasma corticosterone, ng/ml | No. of pulses | Pulse, amplitude, ng/ml |
|---|---|---|---|
| 24-h cycle | |||
| ENDO | 24.5 ± 4.2* | 15.1 ± 1.7** | 54.4 ± 6.2** |
| SALINE | 7.5 ± 1.5 | 6.8 ± 1.0 | 32.9 ± 3.1 |
| First 6 h of light phase (0500–1100) | |||
| ENDO | 17.9 ± 5.7* | 3.3 ± 0.4** | 41.0 ± 4.4** |
| SALINE | 5.7 ± 2.3 | 0.8 ± 0.3 | 15.3 ± 4.4 |
| First 6 h of dark phase (1900–0100) | |||
| ENDO | 35.4 ± 5.0* | 5.8 ± 0.4** | 64.1 ± 6.1** |
| SALINE | 11.3 ± 2.0 | 2.0 ± 0.3 | 29.6 ± 5.6 |
Basal corticosterone was analyzed over 24 h and during the first 6 h of the light phase (nadir, 0500–1100) and the first 6 h of the dark phase (acrophase, 1900–0100) for ENDOS (n = 14) and SALINE (n = 12) animals. Data are expressed as means ± SEM for corticosterone levels, total number of pulses, and pulse amplitude of data points contributing to pulses. ENDO animals exhibit greater mean levels of corticosterone, mean number of pulses, and mean pulse amplitude over 24 h and in each of the light and dark phases of the light cycle. *, P < 0.01; **, P < 0.001.