Fig. 2.

A 39-year-old female patient with McCune-Albright syndrome (pituitary adenoma, fibrous dysplasia, and multinodular thyroid goiter) underwent multisession gamma knife radiosurgery (GKRS) (20 Gy in 4 fractions). Magnetic resonance images before (A) and 23 months after GKRS (B) reveal tumor shrinkage. The patient's growth hormone (GH) levels were followed over the course of treatment. The graph (C) shows continually decreasing levels, finally approaching normal range without medical treatment.