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. 2008 Dec 8;3(12):e3887. doi: 10.1371/journal.pone.0003887

Table 6. Contribution (%) of genetic (heritability, h2) and house (c2) effects to variability in malaria and non-malaria clinical and biological phenotypes of P. falciparum (Pf) and P. vivax (Pv).

Phenotype Acronym N Genetic effect House effect
h2 (S.E.), p-value c2 (S.E.), p-value
A. Clinical phenotypes
Number of visits Pf+ PFA 2018 12.4 (5.7), 0.009 4.6 (2.9), 0.05 a
Number of non-malaria fever visits NMF 2018 NE, NS 8.7 (2.9), 7 × 10−4
Number of visits Pv+ PVA 2018 20.8 (3.6), 4.6 × 10−4 NE, NS
B. Parasite biological phenotypes
Pf max parasite density mx-PFD 857 23.7 (7.9), 1.5 × 10−4 NE, NS
Pf parasite densities PFD 857 20.4 (4.3) NE, NS
Pv max parasite density mx-PVD 470 19.1 (10.5), 0.02 NE, NS
Pv parasite densities PVD 470 14.9 (4.6) NE, NS

h2, variance due to genetics, c2, variance due to house effect, S.E. the standard error; NS, not significant (p-value>0.05); NE, not estimated.

a

Retained because of marginal significance.