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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Exp Neurol. 2007 Dec 15;210(2):549–559. doi: 10.1016/j.expneurol.2007.12.003

Table 2.

The effects of reperfusion and the drug AHA on EBA- and collagen IV-immunoreactive microvessels in striatum.

EBA- immunoreactive Collagen IV-immunoreactive
Groups Total micro vascular area (μm2)/mm2 tissue Average microvascular size (μm2/profile) Total Micro vascular area (μm2)/mm2 tissue Average microvascular size (μm2/profile)
Sham 39.4 ± 14.7 0.17 ± 0.03 55.5 ± 8.6 0.23 ± 0.06
PMCAO 5 h 21.2 ± 3.9& 0.11 ± 0.02& 43.2 ± 2.7& 0.19 ± 0.02
PMCAO 8 h 20.0 ± 3.6& 0.09 ± 0.02&& 42.0 ± 3.8& 0.16 ± 0.01
Isch 5 h/R 3 h 12.9 ± 5.7* 0.08 ± 0.01 31.3 ± 3.6** 0.12 ± 0.02*
Isch 5 h/R 3 h + AHA 19.1 ± 6.9 0.08 ± 0.02 35.0 ± 1.8 0.14 ± 0.02

PMCAO: permanent middle cerebral artery occlusion. Isch: ischemia. R: reperfusion (n=4). AHA: MMP blocker.

&

p < 0.05,

&&

p < 0.01 compared with Sham group.

*

p < 0.05,

**

p < 0.01 compared with PMCAO 8h group.