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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Cancer Invest. 2008 Nov;26(9):956–963. doi: 10.1080/07357900802132550

Table 2.

Patient characteristics

MOSAICa NSABP C-07b
Characteristics All patients FOLFOX (N=1123) FL (N=1123) FLOX (N=1200) FULV (N=1207)
Age
    Median, years 61 60 59.0 59.0
    < 65 years, % 64.4 66.2 68.9 67.0
Sex, %
    Male 56.1 52.4 55.3 57.8
    Female 43.9 47.6 44.7 42.2
T stage, %c
    T1 0.0 0.0 2.8 2.5
    T2 4.5 4.8 8.6 10.0
    T3 76.0 75.9 81.8 79.6
    T4 19.0 18.5 6.8 6.9
    Unknown 0.5 0.8 0.3 0.7
Nodal status, %c
    0 (stage II) 40.2 39.9 28.8 28.8
    1–4 44.4 45.7 52.6 51.5
    5+ 15.1 14.2 18.0 19.5
    Unknown 0.2 0.2 0.2 0.3
a

André, T et al. N Eng J Med. 2004, 350:2343–2351.

b

Kuebler, JP et al. J Clin Oncol. 2007, 25:2198–2204.

c

The distribution of positive nodes and T stage are the only patient characteristics significantly different between the two trials (p<0.0001 for each).