Figure 4.

Annotation editor window showing the analysis of a potential PKS–NRPS hybrid cluster from a marine metagenomic sequence. The following coloring is used: genes (red), PKS protein domains (green) and NRPS protein domains (blue). Although seven genes are shown, the distribution of domains between genes suggest that sequencing errors have occurred. The three boxes indicate the positions of the probable genes. The first gene has one frameshift, the second gene has two frameshifts and the third gene has an anomalous stop codon (ringed in black) in it. The positions where two AT domains would be expected are also ringed (in yelow).