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. 2008 Oct 25;36(21):6825–6834. doi: 10.1093/nar/gkn774

Table 1.

The average ΔTms observed for all drug and IRE combinations

Ligand H-chain L-chain G23I-IRE U10C-IRE U6C-IRE C8A-IRE U6C-U10C-IRE
5 µM DOX 2.5 2.7 4.7 3.7 2.6 3.9 1.0
20 µM DOX 9.9 10.1 10.3 6.8 6.5 7.9 5.5
5 µM DAU 0.5 3.5 3.8 1.7 1.5 2.9 0.5
20 µM DAU 5.7 6.5 7.3 4.7 4.0 5.9 1.5

Average Tm values can be found in the Supplementary Material (Table S1).