Table 4. Adjusted Odds Ratios (ORs) and Associated 95% CIs for Clinical Outcome at 3 Months^*.

	Tier 1		Tier 2		Overall
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
mRS score=0–1 or return to baseline†	0.19 (0.02–1.84)	0.15	0.64 (0.13–3.30)	0.60	0.56 (0.19–1.63)	0.29
Barthel index ≤95†	0.24 (0.01–4.60)	0.34	0.28 (0.04–1.75)	0.17	0.46 (0.14–1.53)	0.20
Glasgow outcome score=0†	1.90 (0.25–14.76)	0.54	0.55 (0.11–2.91)	0.48	1.03 (0.36–3.00)	0.95
Survival at 90 days	0.56 (0.01–33.3)	0.78	0.35 (0.02–6.41)	0.48	0.95 (0.19–4.81)	0.95
Survival at 7 days	Not estimable		Not estimable		0.41 (0.04–4.05)	0.45
Any ICH	0.18 (0.02–1.97)	0.16	0.23 (0.01–5.30)	0.36	0.28 (0.06–1.23)	0.09
NIHSS score decrease ≥4 in 24 hours	0.51 (0.06–4.18)	0.53	0.77 (0.16–3.69)	0.74	0.61 (0.20–1.86)	0.38
NIHSS score ≤2 at 24 hours	0.20 (0.01–20.8)	0.50	0.34 (0.05–2.34)	0.27	0.70 (0.17–2.87)	0.62

^*Analysis controlled for covariates of age, baseline NIHSS score, baseline mRS score, time to treatment, history of diabetes, age×NIHSS interaction, baseline glucose, and baseline systolic and diastolic blood pressures.

^†Deaths (n=18) and missing (n=4) patients were coded as “bad” outcome.