Table 6. Outcome Variables: CLEAR Trial Combination Pts Versus NINDS Stroke Trial rt-PA and Control Pts.

	CLEAR	NINDS rt-PA	P Value	CLEAR	NINDS Control	P Value
n or N	69	115		69	151
mRS score 0–1 or return to baseline*	21 (30%)	46 (40%)	0.19	21 (30%)	36 (24%)	0.30
Barthel index ≤95*	32 (46%)	53 (46%)	0.97	32 (46%)	57 (38%)	0.23
Glasgow outcome score=0*	28 (41%)	47 (41%)	0.97	28 (41%)	44 (29%)	0.09
Symptomatic ICH	1 (1%)	9 (8%)	0.08	1 (1%)	2 (1%)	1.0
Any ICH	8 (12%)	13 (11%)	0.95	8 (12%)	8 (5%)	0.10
Death at 90 days	15 (22%)	21 (18%)	0.56	15 (22%)	31 (20%)	0.84
Death at 7 days	9 (13%)	9 (8%)	0.25	9 (13%)	14 (9%)	0.40
NIHSS score decrease ≥4 in 24 hours*	29 (42%)	47 (41%)	0.88	29 (42%)	57 (38%)	0.55
NIHSS score ≤2 at 24 hours*	9 (13%)	15 (13%)	1.0	9 (13%)	8 (5%)	0.04

Data expressed as n (%).

^*Deaths and missing patients were coded as “bad” outcome.