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. Author manuscript; available in PMC: 2008 Nov 27.
Published in final edited form as: Mol Cell Neurosci. 2008 Feb 13;38(1):43–52. doi: 10.1016/j.mcn.2008.01.013

Fig. 7.

Fig. 7

Expression of the α5 integrin subunit on angiogenic capillaries in the hypoxic CNS. Dual-color immunofluorescence was performed on frozen sections of cerebral cortex taken from mice exposed to 4-day hypobaric hypoxia, using monoclonal antibodies specific for the MECA-32 antigen (Cy-3) or the α5 integrin subunit (FITC), as described in Experimental methods. Scale bar=50 μm. Note that capillaries that stained positive for the MECA-32 antigen, also stained positive for the α5 integrin subunit, confirming that the α5 integrin subunit is expressed by angiogenic endothelial cells within the hypoxic CNS.