Table 2.
Regression coefficients and probability values to determine the association between seminal parameters and exposure and time of exposure to ethylated OP metabolites.
| Exposure to pesticides (β ± SEM) | P | P* adjusted | Time of exposure to pesticides (β ± SEM) | P | P* adjusted | |
| Time of liquefaction minutes | -1.53 ± 1.74 | 0.38 | 0.75 | 0.11 ± 0.31 | 0.71 | 0.93 |
| Seminal Volume mL | -0.72 ± 0.31 | 0.02 | 0.12 | -0.09 ± 0.06 | 0.15 | 0.28 |
| pH | 0.29 ± 0.09 | 0.002 | 0.002 | 0.03 ± 0.02 | 0.07 | 0.001 |
| Log Corrected fructose | -0.17 ± 0.09 | 0.06 | 0.15 | -0.04 ± 0.01 | 0.01 | 0.53 |
| Log Seminal zinc | -0.05 ± 0.09 | 0.58 | 0.30 | -0.02 ± 0.02 | 0.26 | 0.38 |
| Log sperms/mL | -0.14 ± 0.12 | 0.25 | 0.84 | -0.02 ± 0.02 | 0.44 | 0.89 |
| Log sperms/ejaculum | -0.24 ± 0.15 | 0.10 | 0.60 | -0.04 ± 0.03 | 0.15 | 0.80 |
| Sperm Vitality % | 2.07 ± 1.79 | 0.25 | 0.06 | -0.21 ± 0.32 | 0.51 | 0.13 |
| Log motility grade 3 (%) | -0.02 ± 0.09 | 0.78 | 0.71 | -0.02 ± 0.02 | 0.14 | 0.82 |
| Log motility grade 3 + 2 (%) | -0.05 ± 0.05 | 0.32 | 1.00 | -0.02 ± 0.01 | 0.13 | 0.74 |
| Sperm with normal morphology (%) | -7.65 ± 2.16 | 0.001 | 0.76 | -1.04 ± 0.42 | 0.01 | 0.42 |
| Immature sperm (%) | 1.89 ± 1.48 | 0.21 | 1.00 | 0.17 ± 0.26 | 0.51 | 0.50 |
| Log Seminal leucocytes | 0.59 ± 0.09 | 0.00 | 1.00 | 0.02 ± 0.02 | 0.36 | 0.97 |
| Serum testosterone (ng/mL) | -0.62 ± 0.41 | 0.13 | 0.69 | -0.10 ± 0.07 | 0.16 | 0.99 |
| Log Serum estradiol (pg/ml) | 0.06 ± 0.07 | 0.43 | 0.26 | 0.03 ± 0.01 | 0.02 | 0.65 |
| Log Serum FSH (mIU/mL) | 0.17 ± 0.18 | 0.34 | 0.86 | 0.01 ± 0.03 | 0.72 | 1.00 |
| Log Serum LH (mIU/mL) | -0.37 ± 0.21 | 0.07 | 0.97 | -0.10 ± 0.03 | 0.01 | 0.99 |
| Log T/E2 (ng/pg) | -0.11 ± 0.07 | 0.12 | 0.18 | -0.04 ± 0.01 | 0.01 | 0.63 |
| Log T/LH (ng/mIU) | 0.32 ± 0.20 | 0.13 | 1.00 | 0.01 ± 0.03 | 0.01 | 0.85 |
Regressions adjusted for age and alcohol consumption. Exposure to pesticide: 0 = non exposed; 1 = exposed. Ethylated metabolites of OPs: 0 = non detectable; 1 = over limit of detection. Time of exposure to pesticides (continuous variable). β ± SEM: Coefficient of regression ± Standard error of the mean. Data with non parametric behavior were log-transformed in order to performed linear regression analyses. *Holm adjustment.
+Analyses were performed after controlling for urine levels of ethylated OP metabolites, respectively.