Table 3.
Mouse | Meningitis | PV Cuffing | Inflammatory Lesions | Calcifications | Cysts | Inflammation With Cysts | |||||||||||||||
Co | D | H | Ce | Co | D | H | Ce | Co | D | H | Ce | Co | D | H | Ce | Co | D | H | Ce | ||
U1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
U2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
U3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
U4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
U5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
U6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
I1 | 2 | 1 | 2 | 2 | 0 | 2 | 4 | 0 | 0 | 4 | 0 | 0 | 4 | 4 | 7 | 1 | 0 | 1 | 0 | 0 | 0 |
I2 | 1 | 1 | 1 | 2 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
I3 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 2 | 3 | 2 | 0 | 0 | 0 | 1 | 0 |
I4 | 2 | 1 | 3 | 2 | 2 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 5 | 1 | 0 | 0 | 1 | 1 | 0 |
I5 | 3 | 1 | 2 | 1 | 0 | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 3 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | 0 |
I6 | 3 | 1 | 1 | 3 | 1 | 1 | 1 | 4 | 0 | 0 | 2 | 0 | 3 | 2 | 2 | 2 | 1 | 0 | 0 | 1 | 0 |
I7 | 3 | 1 | 2 | 2 | 2 | 4 | 3 | 2 | 0 | 0 | 0 | 0 | 2 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
I8 | 1 | 1 | 1 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Abbreviations: U = uninfected, I = infected, U or I is followed by mouse number; Co = Cortex; D = Diencephalon; H = Hippocampus; Ce = Cerebellum
Scoring System: Meningitis scored 1 = mild; 2 = moderate; 3 = severe; PV cuffing 1 = mild; 2 = moderate; 3 = severe; Inflammatory Lesions scored according to number of lesions identified in one section; Calcifications Scored according to number of calcifications identified in one section; Cysts scored according to number of cysts identified in one section; Inflammation with cysts scored according to number of cysts adjacent to inflammatory lesion, by implication other cysts were 'sitting' in apparently normal brain.