Table 1. Urinary levels of estrogen compounds in men with prostate cancer and healthy men^*.

No.	Compound	Prostate Cancer (n=14)		Control (n=125)		p-value**
		pmol/ml
		Median	Min-Max	Median	Min-Max
1	Androstenedione	9.0	3.3-21.8	8.3	1.9-24.7
2	Testosterone	2.5	0.9-5.8	2.0	0.1-9.2
3	E1-sulfate	1.4	0.2-14.3	1.4	0.0-17.8
4	E2	12.8	4.9-36.2	11.2	0.0-48.3
5	E1
6	2-OHE2	8.1	3.2-86.1	9.4	1.0-116
7	2-OHE1
8	4-OHE2	6.1	0.4-14.3	7.1	0.0-120.
9	4-OHE1
10	16α-OHE2	106	38-549	114	7-954
11	16α-OHE1
12	2-OCH3E2	35.0	4.8-71.7	23.3	0.6-290
13	2-OCH3E1
14	4-OCH3E2	13.7	4.1-27.8	12.3	1.1-511
15	4-OCH3E1
16	2-OH-OCH3E2
17	2-OH-OCH3E1
18	2-OHE2-1-SG	7.2	1.7-12.7	5.6	1.0-27.4
19	2-OHE2-4-SG
20	2-OHE1-1-SG
21	2-OHE1-4-SG
22	2-OHE2-1+4-Cys
23	2-OHE1-1-Cys
24	2-OHE1-4-Cys
25	2-OHE2-1-NAcCys
26	2-OHE2-4-NAcCys
27	2-OHE1-1-NAcCys
28	2-OHE1-4-NAcCys
29	4-OHE2-2-SG	4-OHE2-2-Cys	3.2	0.8-6.5	3.6	0.4-18.7
30	4-OHE1-2-SG
31	4-OHE2-2-Cys
32	4-OHE1-2-Cys
33	4-OHE2-2-NAcCys
34	4-OHE1-2-NAcCys
35	4-OHE2-1-N7Gua	0.7	0.4-1.6	0.3	0.0-2.9	0.0004
36	4-OHE1-1-N7Gua
37	4-OHE2-1-N3Ade	0.4	0.1-3.1	0.2	0.0-3.0	0.056
38	4-OHE1-1-N3Ade
39	2-OHE2-6-N3Ade	0.2	0.0-1.8	0.0	0.0-1.8	0.0014
40	2-OHE1-6-N3Ade

^*The values reported in this table are the sum of the E₁ and E₂ forms of each metabolite [for example, 2-OHE₁(E₂)], the sum of the thiol conjugates of 2-OHE₁(E₂), the sum of the thiol conjugates of 4-OHE₁(E₂), and the sum of the E₁ and E₂ forms of each depurinating DNA adduct.

^**p-value for comparing control vs Pca by using the Mann-Whitney test.