Figure 6.
Effects of 4-AP on electrical and mechanical activity. A. Retinal MVSM cell membrane potential measured in current-clamp mode before, during and after washout of 4-AP. Solid black line represents the average trace obtained from 5 arterioles and the dashed lines above and below represent the S.E.M. B. Digital images of a vessel exposed to 4-AP (10 mM). In the presence of 4-AP some cells undergo small contractions (arrows in centre image). Movie 1 shows the contractions induced by 4-AP in this vessel.