Table 1.
HIV-1 Isolate | Date of Blood Sample | CD4+ T-Cell Count (Cells/μl) | Plasma Viral Load (RNA Copies/ml) | Coreceptor Usage of HIV-1 Isolate* | Clinical History* |
---|---|---|---|---|---|
D36 II | 5/1995 | NT | 1400 | R5X4 | Diagnosed with HIVD 12/1998 |
D36 V | 7/1996 | 414 | 2600 | R5X4 | |
D36 VIII | 5/1997 | 540 | 4000 | R5X4 | ABC, AZT, NVP (1/1999-9/2004) |
D36 IX | 12/1997 | 390 | 7500 | R5X4 | |
D36 X | 7/1998 | 325 | NT | R5X4 | ABC, NVP, 3TC (9/2004-present) |
D36 XI | 1/1999 | 160 | 9900 | R5X4 |
CD4+ T-cells were measured by flow cytometry. Plasma HIV-1 RNA was measured by COBAS Amplicor HIV-1 Monitor Version 1.0 (Roche Molecular Diagnostic Systems, Branchburg, N.J.). NT, not tested; HIVD, HIV-associated dementia; ABC, abavavir; AZT, zidovudine; NVP, nevirapine; 3TC, lamivudine. *These results have been reported previously [31, 18].