Abstract
Cytomegalovirus (CMV) inclusions were discovered at autopsy in the thyroid follicles in five immunocompromised adults, four of whom had acquired immune deficiency syndrome (AIDS). Although reports of viral infections of the thyroid are uncommon in adults, our experience suggests that the thyroid gland may be commonly involved in patients with disseminated CMV, and the possibility exists that CMV infection of the thyroid has the potential to cause clinical dysfunction.
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- Burt A. D., Scott G., Shiach C. R., Isles C. G. Acquired immunodeficiency syndrome in a patient with no known risk factors: a pathological study. J Clin Pathol. 1984 Apr;37(4):471–474. doi: 10.1136/jcp.37.4.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chopra I. J., Solomon D. H., Hepner G. W., Morgenstein A. A. Misleadingly low free thyroxine index and usefulness of reverse triiodothyronine measurement in nonthyroidal illnesses. Ann Intern Med. 1979 Jun;90(6):905–912. doi: 10.7326/0003-4819-90-6-905. [DOI] [PubMed] [Google Scholar]
- Craighead J. E. Pulmonary cytomegalovirus infection in the adult. Am J Pathol. 1971 Jun;63(3):487–504. [PMC free article] [PubMed] [Google Scholar]
- Hui A. N., Koss M. N., Meyer P. R. Necropsy findings in acquired immunodeficiency syndrome: a comparison of premortem diagnoses with postmortem findings. Hum Pathol. 1984 Jul;15(7):670–676. doi: 10.1016/s0046-8177(84)80293-2. [DOI] [PubMed] [Google Scholar]
- Macasaet F. F., Holley K. E., Smith T. F., Keys T. F. Cytomegalovirus studies of autopsy tissue. II. Incidence of inclusion bodies and related pathologic data. Am J Clin Pathol. 1975 Jun;63(6):859–865. doi: 10.1093/ajcp/63.6.859. [DOI] [PubMed] [Google Scholar]
- Meiselman M. S., Cello J. P., Margaretten W. Cytomegalovirus colitis. Report of the clinical, endoscopic, and pathologic findings in two patients with the acquired immune deficiency syndrome. Gastroenterology. 1985 Jan;88(1 Pt 1):171–175. doi: 10.1016/s0016-5085(85)80150-5. [DOI] [PubMed] [Google Scholar]
- Melmed S., Geola F. L., Reed A. W., Pekary A. E., Park J., Hershman J. M. A comparison of methods for assessing thyroid function in nonthyroidal illness. J Clin Endocrinol Metab. 1982 Feb;54(2):300–306. doi: 10.1210/jcem-54-2-300. [DOI] [PubMed] [Google Scholar]
- Myerson D., Hackman R. C., Nelson J. A., Ward D. C., McDougall J. K. Widespread presence of histologically occult cytomegalovirus. Hum Pathol. 1984 May;15(5):430–439. doi: 10.1016/s0046-8177(84)80076-3. [DOI] [PubMed] [Google Scholar]
- Palestine A. G., Rodrigues M. M., Macher A. M., Chan C. C., Lane H. C., Fauci A. S., Masur H., Longo D., Reichert C. M., Steis R. Ophthalmic involvement in acquired immunodeficiency syndrome. Ophthalmology. 1984 Sep;91(9):1092–1099. doi: 10.1016/s0161-6420(84)34201-4. [DOI] [PubMed] [Google Scholar]
- Salisbury S., Embil J. A. Graves disease following congenital cytomegalovirus infection. J Pediatr. 1978 Jun;92(6):954–955. doi: 10.1016/s0022-3476(78)80373-4. [DOI] [PubMed] [Google Scholar]
- Stancek D., Ciampor F., Mucha V., Hnilica P., Stancekova M. Morphological, cytological and biological observations on viruses isolated from patients with subacute thyroiditis de Quervain. Acta Virol. 1976 Jun;20(3):183–188. [PubMed] [Google Scholar]
- Volpé R. Subacute (de Quervain's) thyroiditis. Clin Endocrinol Metab. 1979 Mar;8(1):81–95. doi: 10.1016/s0300-595x(79)80011-0. [DOI] [PubMed] [Google Scholar]
- Welch K., Finkbeiner W., Alpers C. E., Blumenfeld W., Davis R. L., Smuckler E. A., Beckstead J. H. Autopsy findings in the acquired immune deficiency syndrome. JAMA. 1984 Sep 7;252(9):1152–1159. [PubMed] [Google Scholar]
- Werner J., Gelderblom H. Isolation of foamy virus from patients with de Quervain thyroiditis. Lancet. 1979 Aug 4;2(8136):258–259. doi: 10.1016/s0140-6736(79)90275-7. [DOI] [PubMed] [Google Scholar]