Table 1.
Expression of members of the IEG family in the Cx, BF and Hy.
Candidate gene expression during recovery sleep (RS)* and PGD2- and CGS21680-induced sleep.
| Cerebral Cortex | Basal Forebrain | Hypothalamus | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene | RS | PGD2 | CGS | RS | PGD2 | CGS | RS | PGD2 | CGS |
| arc | – | ↓↓ | ↓↓ | – | ↓↓ | ↓↓ | – | ↓↓ | ↓↓ |
| c-fos | – | – | – | – | ↑↑↑↑ | ↑↑↑↑↑↑ | – | ↑↑↑ | ↑↑↑↑ |
| cjun | – | – | ↑↑ | – | ↑↑ | ↑↑ | – | ↑↑ | ↑ |
| egr-3 | ↑↑ | – | – | – | – | – | – | – | – |
| fra-1 | – | – | – | – | – | ↑↑ | – | – | ↑↑ |
| fra-2 | ↑ | – | – | ↑↑ | ↑↑↑↑ | ↑↑↑↑↑ | ↑↑ | ↑↑↑ | ↑↑↑↑ |
| grp78 | ↑ | – | – | – | – | – | – | – | – |
| grp94 | ↑ | – | ↑↑ | – | – | – | – | – | – |
| jun-B | – | – | – | – | ↑↑↑ | ↑↑↑↑ | – | ↑↑↑↑ | ↑↑↑↑↑↑ |
| jun-D | – | – | – | – | – | – | – | – | – |
| ngfi-a | – | – | – | – | – | – | – | – | ↑↑ |
| ngfi-b | – | – | – | – | – | ↑↑↑ | – | – | ↑↑↑↑↑ |
| nr4a3 | ↑ | – | – | ↑↑ | – | – | – | – | ↑↑↑ |
Number of arrows indicates x-fold change as determined by real-time RT-PCR analysis:
indicates gene is significantly upregulated but the magnitude is 1.5-fold or less.
indicates gene is significantly upregulated and the magnitude is 1.5- to 2.5-fold.
indicates gene is significantly upregulated and the magnitude is 2.5- to 3.5-fold.
indicates gene is significantly upregulated and the magnitude is 3.5- to 4.5-fold.
indicates gene is significantly upregulated and the magnitude is 4.5- to 5.5-fold.
indicates gene is significantly upregulated and the magnitude is 5.5- to 6.5-fold.
indicates gene is significantly downregulated but the magnitude is 1.5-fold or less.
indicates gene is significantly downregulated and the magnitude is 1.5- to 2.5-fold.
indicates gene is significantly downregulated and the magnitude is 2.5- to 3.5-fold.
No change relative to time-matched control.
Data from RS have been reported previously in Terao et al. (2006) and are included here for comparison.