Table 5.
Univariate analysis of the primary cohort - donor, recipient and transplant center characteristics associated with donor medical complexity
| Primary cohort n=4819 |
Complete cohort n=9319 |
|||||
|---|---|---|---|---|---|---|
| Donor attribute (binary) |
OR | C.I. | p | OR | C.I. | p |
| Parent | 1.25 | 1.00-1.55 | 0.049 | 1.21 | 1.03-1.43 | 0.02 |
| Spouse | 1.33 | 1.11-1.58 | <0.01 | 1.23 | 1.07-1.41 | <0.01 |
| Female | 0.92 | 0.81-1.03 | 0.16 | 0.90 | 0.91-0.98 | 0.02 |
| Hispanic | 1.05 | 0.88-1.25 | 0.60 | 0.94 | 0.82-1.09 | 0.43 |
| Black | 1.26 | 1.07-1.49 | <0.01 | 1.12 | 0.98-1.28 | 0.09 |
| Low education * | 1.21 | 1.06-1.38 | <0.01 | 1.18 | 1.07-1.32 | <0.01 |
| Non US citizen | 0.68 | 0.50-0.91 | <0.01 | 0.74 | 0.59-0.94 | 0.01 |
|
Donor attribute (continuous) |
Complex |
Non- complex |
p | Complex |
Non- complex |
p |
| Age | 41.1 | 39.4 | <0.01 | 41.8 | 39.9 | <0.01 |
|
Recipient attribute (binary) |
OR | C.I. | p | OR | C.I. | p |
| Female | 1.10 | 0.97-1.24 | 0.13 | 1.09 | 0.99-1.20 | 0.08 |
| Hispanic | 1.05 | 0.88-1.25 | 0.57 | 0.96 | 0.83-1.11 | 0.55 |
| Black | 1.25 | 1.06-1.46 | <0.01 | 1.11 | 0.98-1.26 | 0.11 |
| Low education * | 1.08 | 0.95-1.22 | 0.23 | 1.08 | 0.98-1.19 | 0.13 |
| Cause ESRD: Diabetes |
1.12 | 0.97-1.29 | 0.14 | 1.12 | 1.00-1.26 | 0.045 |
| Dialysis | 1.11 | 0.98-1.26 | 0.12 | 1.09 | 0.99-1.20 | 0.09 |
| Prior kidney transplant |
0.99 | 0.81-1.21 | 0.94 | 0.93 | 0.79-1.09 | 0.38 |
| Blood type O | 0.92 | 0.82-1.04 | 0.21 | 0.95 | 0.87-1.05 | 0.32 |
|
Recipient attribute (continuous) |
Complex |
Non- complex |
P | Complex |
Non- complex |
p |
| Age (years) | 47.3 | 46.4 | 0.03 | 47.2 | 46.4 | 0.02 |
| Mean duration wait-list (days) ** |
313.0 | 333.6 | 0.055 | 312.2 | 324.0 | 0.14 |
| Peak PRA** | 10.1 | 9.7 | 0.54 | 9.3 | 9.8 | 0.27 |
|
Center attribute (Ordinal) |
||||||
|
% Complex donors |
p |
% Complex donors |
p | |||
| Category of center volume |
||||||
| Low | 28.7 | Reference | 24.3 | Reference | ||
| Intermediate | 31.9 | 0.19 | 24.6 | 0.88 | ||
| High | 33.5 | 0.04 | 24.0 | 0.88 | ||
| Category of market competitiveness *** |
||||||
| Low | 34.8 | 0.01 | 25.3 | 0.11 | ||
| Intermediate | 32.4 | 0.22 | 23.7 | 0.81 | ||
| High | 30.4 | Reference | 23.5 | Reference | ||
|
Center attribute (continuous) |
Complex |
Non- Complex |
p | complex |
Non- complex |
p |
| Proportion of live donors/total donors |
43.7% | 42.7% | 0.01 | 43.7% | 42.8% | <0.01 |
| Median days of wait-list time for deceased donor kidney in the center’s DSA |
1409.3 | 1464.8 | <0.01 | 1404.9 | 1462.6 | <0.01 |
Abbreviations ESRD: End-stage renal disease; PRA=panel reactive antigen; DSA=donor service area
*
Defined as no years of college education
**
Mean values were imputed for missing data on duration of waiting list time and peak PRA
***
Market competitiveness as measured by the Herfindahl-Hirschmann index; the “market” here is centers performing renal transplants within a single donor service area