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Corticosterone induction by exposure to light in early night (ZT16). Serum corticosterone from untreated mice (n=4) and mice subjected to a light treatment (15μW/cm2, 30 minute duration, n=4) were determined by ELISA. WT mice respond to the light with a significance increase in circulating corticosterone concentration (283.60±28.84 ng/ml; P<0.05), but VIP KO mice failed to show a significant corticosterone response (33.42±17.79 ng/ml).
