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. Author manuscript; available in PMC: 2008 Nov 29.
Published in final edited form as: J Neurophysiol. 2004 Aug 25;93(1):35–43. doi: 10.1152/jn.00603.2004

FIG. 4.

FIG. 4

Enhancement of movement-related discharge after GABAA antagonists. A: small, steplike increase in discharge of a CN neuron (P34U6) recorded before injection. B: after 1 μl bicuculline, another neuron (P34U8) increased its firing rate by more than 140 spikes/s. This cell was recorded within 250 μm of the neuron shown above. C: 40 spikes/s DOM before injection (P42U1). D: after the GABAA antagonist GABAzine (SR95531), the neuron P42U2 showed an increase in firing of 46 spikes/s, which began 220 ms before the onset of reach. For this and subsequent figures, the horizontal dashed line indicates spontaneous firing rate, and the vertical dashed line marks the onset of modulation. Median times at which the reach and button (or grip) phases of the task ended are indicated by the heavy vertical lines within the box under the reach-aligned PETH. Shaded regions show the 25th and 75th percentiles of the variation in these times.