Sinusoidal ERG. Blue and red lines refer to rd10 mice, aged P18 and P26, respectively. Black lines refer to wt, age-matched animals. Gray lines represent the sinusoidal light stimulus.
Left panel: sinusoidal ERG responses to 4 different temporal frequencies.
Right panel: Kinetic analysis of ERG responses, obtained from rd10 mice aged P18 (A; n=8) and P26 (B; n=8) and from age-matched wt mice (n=8, black lines), using light stimuli sinusoidally modulated in time, from 0.3 to 30 Hz. The amplitude of the response, plotted as a function of the temporal frequency of the stimulus (attenuation characteristics), appears suppressed in the frequency range of 2–10 Hz.