FIGURE 1.
Glycogen and glycogen phosphate levels increase with age in the absence of laforin. A, glycogen phosphate levels in muscle glycogen from wild type (WT) and Epm2a–/– mice at 3 months (open bars) and 9–12 months (filled bars). *, p < 0.001 versus wild type; #, p < 0.01 versus 3-month-old Epm2a–/– (n = 7–8). B, skeletal muscle glycogen content levels in wild type and Epm2a–/– mice. *, p < 0.001 versus WT and 3-month-old Epm2a–/– (n = 11–15). C, brain glycogen content in WT and Epm2a–/– mice. *, p = 0.0001 versus WT; #, p < 0.002 versus 3-month-old Epm2a–/– (n = 3–4).
