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. 2008 Oct;20(10):2603–2618. doi: 10.1105/tpc.108.060913

Figure 1.

Figure 1.

Schematic Diagram of GA Metabolism and Response Pathways.

Conversion of GA12 and GA53 to GA110 and GA97, respectively, by 2β-hydroxylation was demonstrated experimentally only for GA2ox6 in this study. GA2ox5, GA2ox6, and GA2ox9 are proposed to have similar functions due to the presence of three conserved motifs unique to C20 GA2oxs. Inactivation of C19-GA precursors, GA1 and GA4 by the C19 GA2oxs, GA2ox1 and GA2ox3, in rice was demonstrated experimentally (Sakamoto et al., 2001; Sakai et al., 2003). Bioactive GA positively regulates germination, stem and root elongation, and flower development but negatively regulates OSH1 and TB1 that control tillering. GA also negatively regulates adventitious root development.